WIM G.J. Hol: search on Z-Library

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1

A general protocol for the generation of Nanobodies for structural biology

Pardon, Els, Laeremans, Toon, Triest, Sarah, Rasmussen, Søren G F, Wohlkönig, Alexandre, Ruf, Armin, Muyldermans, Serge, Hol, Wim G J, Kobilka, Brian K, Steyaert, Jan

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

2

Soil microbial species loss affects plant biomass and survival of an introduced bacterial strain, but not inducible plant defences

Kurm, Viola, van der Putten, Wim H, Pineda, Ana, Hol, W H Gera

Journal:

Annals of Botany

Year:

2018

Language:

english

File:

PDF, 571 KB

english, 2018

3

The dipoles of the alpha-helix and the beta-sheet: Their role in the folding of proteins

Louis M. Halie, Wim G. J. Hol

Journal:

European Biophysics Journal

Year:

1981

Language:

english

File:

PDF, 65 KB

english, 1981

4

Reduction of rare soil microbes modifies plant–herbivore interactions

W. H. Gera Hol, Wietse De Boer, Aad J. Termorshuizen, Katrin M. Meyer, Johannes H. M. Schneider, Nicole M. Van Dam, Johannes A. Van Veen, Wim H. Van Der Putten

Journal:

Ecology Letters

Year:

2010

Language:

english

File:

PDF, 270 KB

english, 2010

5

The covalent and tertiary structure of bovine liver rhodanese

Ploegman, Jan H., Drent, Gé, Kalk, Kor H., Hol, Wim G. J., Heinrikson, Robert L., Keim, Philip, Weng, Litai, Russell, John

Journal:

Year:

1978

File:

PDF, 603 KB

1978

6

Secretins: dynamic channels for protein transport across membranes

Konstantin V. Korotkov, Tamir Gonen, Wim G.J. Hol

Journal:

Trends in Biochemical Sciences

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

7

Protein–protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase

Sharmila S Mande, Steve Sarfaty, Mark D Allen, Richard N Perham, Wim GJ Hol

Journal:

Year:

1996

Language:

english

File:

PDF, 1.37 MB

english, 1996

8

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

Rongbao Li, Rachada Sirawaraporn, Penchit Chitnumsub, Worachart Sirawaraporn, Jason Wooden, Francis Athappilly, Stewart Turley, Wim G.J Hol

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

9

The acquisition of tolerance toward cow's milk through probiotic supplementation: A randomized, controlled trial

Hol, Jeroen, van Leer, Eduard H.G., Elink Schuurman, Beatrix E.E., de Ruiter, Lilian F., Samsom, Janneke N., Hop, Wim, Neijens, Herman J., de Jongste, Johan C., Nieuwenhuis, Edward E.S.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

10

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

Cho Yeow Koh, Jessica E. Kim, Sayaka Shibata, Ranae M. Ranade, Mingyan Yu, Jiyun Liu, J. Robert Gillespie, Frederick S. Buckner, Christophe L.M.J. Verlinde, Erkang Fan, Wim G.J. Hol

Journal:

Year:

2012

Language:

english

File:

PDF, 5.12 MB

english, 2012

11

Crystal structure of the full-length ATPase GspE from the Vibrio vulnificus type II secretion system in complex with the cytoplasmic domain of GspL

Lu, Connie, Korotkov, Konstantin V., Hol, Wim G.J.

Journal:

Journal of Structural Biology

Year:

2014

Language:

english

File:

PDF, 3.67 MB

english, 2014

12

Low abundant soil bacteria can be metabolically versatile and fast growing

Kurm, Viola, van der Putten, Wim H, de Boer, Wietse, Naus-Wiezer, Suzanne, Hol, W.H. Gera

Journal:

Year:

2016

Language:

english

File:

PDF, 539 KB

english, 2016

13

From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis

Devine, William G., Diaz-Gonzalez, Rosario, Ceballos-Perez, Gloria, Rojas, Domingo, Satoh, Takashi, Tear, Westley, Ranade, Ranae M., Barros-Álvarez, Ximena, Hol, Wim G. J., Buckner, Frederick S., Nava

Journal:

ACS Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 818 KB

english, 2017

14

Context dependency and saturating effects of loss of rare soil microbes on plant productivity

Hol, W. H. Gera, de Boer, Wietse, de Hollander, Mattias, Kuramae, Eiko E., Meisner, Annelein, van der Putten, Wim H.

Journal:

Frontiers in Plant Science

Year:

2015

Language:

english

File:

PDF, 744 KB

english, 2015

15

A general method of domain closure is applied to phosphoglycerate kinase and the result compared with the crystal structure of a closed conformation of the enzyme

Nagasuma R. Chandra, Hilary Muirhead, J. John Holbrook, Bradley E. Bernstein, Wim G.J. Hol, Richard B. Sessions

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1998

Language:

english

File:

PDF, 424 KB

english, 1998

16

A database method for automated map interpretation in protein crystallography

David J. Diller, Matthew R. Redinbo, Ehmke Pohl, Wim G.J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 880 KB

english, 1999

17

A rapid method for positioning small flexible molecules, nucleic acids, and large protein fragments in experimental electron density maps

David J. Diller, Ehmke Pohl, Matthew R. Redinbo, Bianca T. Hovey, Wim G.J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 602 KB

english, 1999

18

Mutational analysis of the role of ADP-ribosylation activity and GM1 -binding activity in the adjuvant properties of the Escherichia coli heat-labile enterotoxin towards intranasally administered keyhole limpet hemocyanin

Lolke de Haan, Ingeborg K. Feil, Willem R. Verweij, Marijke Holtrop, Wim G. J. Hol, Etienne Agsteribbe, Jan Wilschut

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 146 KB

english, 1998

19

Proteinkristallographie und Computer-Graphik – auf dem Weg zu einer planvollen Arzneimittelentwicklung

Prof. Dr. Wim G. J. Hol

Journal:

Angewandte Chemie

Year:

1986

Language:

german

File:

PDF, 2.35 MB

german, 1986

20

Protein Crystallography and Computer Graphics—toward Rational Drug Design

Journal:

Angewandte Chemie International Edition

Year:

1986

Language:

english

File:

PDF, 1.68 MB

english, 1986

21

Electrostatic interactions between α-helix dipoles in crystals of an uncharged helical undecapeptide

Wim G. J. Hol, Marc C. H. De Maeyer

Journal:

Year:

1984

Language:

english

File:

PDF, 421 KB

english, 1984

22

ChemInform Abstract: Selective Tight Binding Inhibitors of Trypanosomal Glyceraldehyde-3-phosphate Dehydrogenase via Structure-Based Drug Design.

Alex M. Aronov, Christophe L. M. J. Verlinde, Wim G. J. Hol, Michael H. Gelb

Journal:

Year:

1999

File:

PDF, 28 KB

1999

23

Synthesis and Conformational Analysis of 2′-Deoxy-2′-(3-methoxybenzamido)adenosine, a rational-designed inhibitor of trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH)

Serge Van Calenbergh, Elfride Van Den Eeckhout, Piet Herdewijn, André De Bruyn, Christophe Verlinde, Wim Hol, Mia Callens, Arthur Van Aerschot, Jef Rozenski

Journal:

Helvetica Chimica Acta

Year:

1994

Language:

english

File:

PDF, 926 KB

english, 1994

24

3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists: synthesis and crystallographic studies

Daniel D Mitchell, Jason C Pickens, Konstantin Korotkov, Erkang Fan, Wim G.J Hol

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 1.06 MB

english, 2004

25

Biogenesis of peroxisomes and glycosomes: trypanosomatid glycosome assembly is a promising new drug target

Juliette Moyersoen, Jungwoo Choe, Erkang Fan, Wim G.J. Hol, Paul A.M. Michels

Journal:

FEMS Microbiology Reviews

Year:

2004

Language:

english

File:

PDF, 1.28 MB

english, 2004

26

Use of thermal melt curves to assess the quality of enzyme preparations

Gregory J. Crowther, Panqing He, Philip P. Rodenbough, Andrew P. Thomas, Kuzma V. Kovzun, David J. Leibly, Janhavi Bhandari, Lisa J. Castaneda, Wim G.J. Hol, Michael H. Gelb, Alberto J. Napuli, Wesley

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

27

Nonspanning Bivalent Ligands as Improved Surface Receptor Binding Inhibitors of the Cholera Toxin B Pentamer

Jason C. Pickens, Daniel D. Mitchell, Jiyun Liu, Xiaojian Tan, Zhongsheng Zhang, Christophe L.M.J. Verlinde, Wim G.J. Hol, Erkang Fan

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 920 KB

english, 2004

28

Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity

Youngsoo Kim, Wim G.J Hol

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 741 KB

english, 2001

29

Anomalous Differences of Light Elements in Determining Precise Binding Modes of Ligands to Glycerol-3-Phosphate Dehydrogenase

Jungwoo Choe, Stephen Suresh, Goragot Wisedchaisri, Kevin J Kennedy, Michael H Gelb, Wim G.J Hol

Journal:

Chemistry & Biology

Year:

2002

Language:

english

File:

PDF, 460 KB

english, 2002

30

Crystal Structure of a Transition State Mimic for Tdp1 Assembled from Vanadate, DNA, and a Topoisomerase I-Derived Peptide

Douglas R. Davies, Heidrun Interthal, James J. Champoux, Wim G.J. Hol

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 1.05 MB

english, 2003

31

Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins

Juliette Moyersoen, Jungwoo Choe, Abhinav Kumar, Frank G. J. Voncken, Wim G. J. Hol, Paul A. M. Michels

Journal:

Year:

2003

Language:

english

File:

PDF, 242 KB

english, 2003

32

Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: Binding at the active site despite an “open” flexible loop conformation

Christophe L.M.J. Verlinde, Cornelis J. Witmans, Tjaard Pijning, Kor H. Kalk, Wim G.J. Hol, Mia Callens, Fred R. Opperdoes

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 711 KB

english, 1992

33

Crystal structure of deoxygenated limulus polyphemus subunit II hemocyanin at 2.18 Å resolution: Clues for a mechanism for allosteric regulation

Bart Hazes, Kor H. Kalk, WIM G.J. Hol, Karen A. Magnus, Celia Bonaventura, Joseph Bonaventura, Zbigniew Dauter

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 6.38 MB

english, 1993

34

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide

Ethan A. Merritt, Steve Sarfaty, Focco Van Den Akker, Cécile L'Hoir, Joseph A. Martial, Wim G.J. Hol

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 4.37 MB

english, 1994

35

Crystal structure of recombinant human triosephosphate isomerase at 2.8 Å resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme

Shekhar C. Mande, Wim G.J. Hol, Véronique Mainfroid, Karine Goraj, Joseph A. Martial, Kor H. Kalk

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 4.21 MB

english, 1994

36

Protein crystallography and infectious diseases

Christophe L.M.J. Verlinde, Ethan A. Merritt, Focco Van Den Akker, Hidong Kim, Ingeborg Feil, Luis F. Delboni, Shekhar C. Mande, Steve Sarfaty, Philip H. Petra, Wim G.J. Hol

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 10.91 MB

english, 1994

37

Structural diversity in a conserved cholera toxin epitope involved in ganglioside binding

Menachem Shoham, Tali Scherf, Jacob Anglister, Michael Levitt, Ethan A. Merritt, Wim G.J. Hol

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 3.54 MB

english, 1995

38

Crystal structure of recombinant triosephosphate isomerase from bacillus stearothermophilus. An analysis of potential thermostability factors in six isomerases with known three-dimensional structures points to the importance of hydrophobic interactions

Luis F. Delboni, Shekhar C. Mande, Stewart Turley, WIM G.J. Hol, Françoise Rentier-Delrue, Véronique Mainfroid, Joseph A. Martial, Frederique M.D. Vellieux

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 2.07 MB

english, 1995

39

Improvement of diffraction quality upon rehydration of dehydrated icosahedral enterococcus faecalis pyruvate dehydrogenase core crystals

Tina Izard, Steve Sarfaty, Adrie Westphal, Arie De Kok, WIM G. J. Hol

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 344 KB

english, 1997

40

Comparison of high-resolution structures of the diphtheria toxin repressor in complex with cobalt and zinc at the cation-anion binding site

Ehmke Pohl, Xiayang Qiu, Lisa M. Must, Randall K. Holmes, Wim G. J. Hol

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 1.23 MB

english, 1997

41

Structural studies of receptor binding by cholera toxin mutants

Ethan A. Merritt, Steve Sarfaty, WIM G.J. Hol, Michael G. Jobling, Randall K. Holmes, T. Chang, Timothy R. Hirst

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 5.35 MB

english, 1997

42

Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant

Focco Van Den Akker, Mariagrazia Pizza, Rino Rappuoli, Wim G. J. Hol

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 2.33 MB

english, 1997

43

Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit

F. Van Den Akker, I. K. Feil, C. Roach, A. A. Platas, E. A. Merritt, Wim G. J. Hol

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 2.12 MB

english, 1997

44

The importance of dynamic light scattering in obtaining multiple crystal forms of trypanosoma brucei PGK

Bradley E. Bernstein, Paul A. M. Michels, Hidong Kim, Philip H. Petra, Wim G. J. Hol

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 456 KB

english, 1998

45

Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum

J. Caruthers, J. Bosch, F. Buckner, W. Van Voorhis, P. Myler, E. Worthey, C. Mehlin, E. Boni, G. DeTitta, J. Luft, A. Lauricella, O. Kalyuzhniy, L. Anderson, F. Zucker, M. Soltis, Wim G. J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2006

Language:

english

File:

PDF, 768 KB

english, 2006

46

Drug design for the third world: A conference report

Eaton E. Lattman, Wim G. J. Hol, Eddy Arnold

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 83 KB

english, 2007

47

Modeling the interaction between aldolase and the thrombospondin-related anonymous protein, a key connection of the malaria parasite invasion machinery

Carlos A. Buscaglia, Wim G. J. Hol, Victor Nussenzweig, Timothy Cardozo

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 428 KB

english, 2007

48

The crystal structure of the “open” and the “closed” conformation of the flexible loop of trypanosomal triosephosphate isomerase

Rik K. Wierenga, Martin E. M. Noble, Johan P. M. Postma, Hillie Groendijk, Kor H. Kalk, Wim G. J. Hol, Fred R. Opperdoes

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 1.69 MB

english, 1991

49

Hexamers of subunit II from Limulus hemocyanin (a 48-mer) have the same quaternary structure as whole Panulirus hemocyanin molecules

Karen A. Magnus, Eaton E. Lattman, Anne Volbeda, Wim G. J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 791 KB

english, 1991

50

The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes

Martin E. M. Noble, Rik K. Wierenga, Anne-Marie Lambeir, Fred R. Opperdoes, Andy-Mark W. H. Thunnissen, Kor H. Kalk, Hillie Groendijk, Wim G. J. Hol

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 1.63 MB

english, 1991